How to Improve Zinc Uptake to Boost Immune Health
Zinc Binding Compounds Boost Immune System
“The long-standing bias against natural over patentable synthetic molecules in the practice of medicine has now resulted in the avoidable premature death of thousands of the most vulnerable individuals and the abrupt and near-complete economic collapse of modern society due to an unwarranted over-response by health authorities, political overseers and sensationalist news media.
The narrow and archaic vaccine-only paradigm to treat infectious diseases has left human populations vulnerable to a highly transmissible … virus … This unprecedented man-made chaos could have been avoided by putting into practice a remedy described … a decade ago.
In 2010 … researchers … reported that the combination of … zinc plus a zinc transport molecule (ionophore) that facilitates zinc’s entry into cells effectively impairs the replication of RNA viruses, like the newly mutated COVID-19 coronavirus, to affect a cure …
This prior discovery appears to validate the recent report6 of Vladimir Zelenko MD, a New York-based physician who has treated 699 consecutive cases of COVID-19 … with complete 100% success. His treatment protocol includes oral zinc, chloroquine as a zinc ionophore and an antibiotic (azithromycin).”
COVID-19 and Zinc Deficiency Share Many Symptoms
Abdominal discomfort or cramping
Loss of smell
Lowered immune function
Reduced lymphocytes (white blood cells)
Increased interleukin-6, indicative of inflammation
Elevated iron storage
“In the present COVID-19 coronavirus epidemic the zinc + ionophore combination could have been employed in a targeted fashion for high-risk groups (elderly, diabetics, smokers, alcohol abusers, immune suppressant and illicit-drug users) as prevention and for curative purposes among patients with severe lung disease.
The family of RNA viruses also includes poliovirus and influenza virus. In other words, zinc therapy would also simultaneously address the seasonal flu viruses also in circulation, something public health authorities strangely paid no attention to this flu season.”
Facilitating Zinc Entry Into Cells Is a Crucial Component
“[This] makes the discovery of an ionophore as important as zinc’s primary role in infection control,” Sardi points out, adding,10 “Such a discovery, if put into practice, would have upset the reigning vaccine paradigm that now predominates in modern medicine. Research dollars would evaporate as a cure for seasonal influenza and coronaviruses … would have been found.”
Other Natural Zinc Transporters — Quercetin and EGCG
“Labile zinc, a tiny fraction of total intracellular zinc that is loosely bound to proteins and easily interchangeable, modulates the activity of numerous signaling and metabolic pathways. Dietary plant polyphenols such as the flavonoids quercetin (QCT) and epigallocatechin-gallate act as antioxidants and as signaling molecules.
Remarkably, the activities of numerous enzymes that are targeted by polyphenols are dependent on zinc. We have previously shown that these polyphenols chelate zinc cations and hypothesized that these flavonoids might be also acting as zinc ionophores, transporting zinc cations through the plasma membrane.
To prove this hypothesis, herein, we have demonstrated the capacity of QCT and epigallocatechin-gallate to rapidly increase labile zinc in mouse hepatocarcinoma Hepa 1-6 cells as well as, for the first time, in liposomes … The ionophore activity of dietary polyphenols may underlay the raising of labile zinc levels triggered in cells by polyphenols and thus many of their biological actions.”
‘Poor Man’s Coronavirus Defense’
- A natural antibiotic such as cinnamon extract or oil of oregano
- Quercetin as a zinc ionophore (to enhance zinc entrance into cells)
- Zinc, up to 30 milligrams per day
- Vitamin B3 (niacin), 25 to 50 mg per day, and selenium to further boost bioavailability of zinc
Zinc + Niacin + Selenium Is a Winning Combo
“Ageing is an inevitable biological process with gradual and spontaneous biochemical and physiological changes and increased susceptibility to diseases.
Some nutritional factors (zinc, niacin, selenium) may remodel these changes leading to a possible escaping of diseases, with the consequence of healthy ageing, because they are involved in improving immune functions, metabolic homeostasis and antioxidant defense.
Experiments … show that zinc is important for immune efficiency (both innate and adaptive), metabolic homeostasis (energy utilization and hormone turnover) and antioxidant activity (SOD enzyme).
Niacin is a precursor of NAD+, the substrate for the activity of DNA repair enzyme PARP-1 and, consequently, may contribute to maintaining genomic stability. Selenium provokes zinc release by metallothioneins (MT), via reduction of glutathione peroxidase.
This fact is crucial in ageing because high MT may be unable to release zinc with subsequent low intracellular free zinc ion availability for immune efficiency, metabolic harmony and antioxidant activity.
Taking into account the existence of zinc transporters … for cellular zinc efflux and influx, respectively, the association between zinc transporters and MT is crucial in maintaining satisfactory intracellular zinc homeostasis in ageing.
Improved immune performance, metabolic homeostasis, antioxidant defense occur in elderly after physiological zinc supplementation … The association ‘zinc plus selenium’ improves humoral immunity in old subjects after influenza vaccination.”